International Journal of Pharma and Bio Sciences
 
 
    ISSN 0975-6299
www.ijpbs.net
RESEARCH ARTICLE
Int J Pharm Bio Sci Volume 7 Issue 3, 2016 (July-Sept), Pages:89 - 94
EVALUATION OF ANTINOCICEPTIVE AND ANTIPYRETIC ACTIVITIES OF SALIX TETRASPERMA ROXBURG
J.H.VIRUPAKSHA,RAMA RAO NADENDLA, M.SATISHKUMAR
DOI:
[Download PDF]
Abstract:

The present study was designed to evaluate antinociceptive and antipyretic activities of leaf extracts of Salix tetrasperma Roxburgh in rodents. The ethanolic and aqueous leaf extracts were tested for antinociceptive and antipyretic activities. Antinociceptive activity was evaluated using thremoceptive models namely eddy’s Hot plate and tail flick by analgesiometer. The antipyretic activity was evaluated using brewer’s yeast induced method. Retreatment with ethanolic and aqueous extracts of Salix tetrasperma leaves at 200 and 400 mg/kg showed significant dose dependent antinociceptive activity in the tested models. Both the extracts lowered the elevated rectal temperature in the brewer’s yeast induced pyretic model in a dose dependent manner. The findings in this study suggest that the ethanolic and aqueous leaf extracts of Salix tetrasperma possesses antinociceptive and antipyretic activity. Thus it provides a scientific evidence for its traditional claim.

Keywords: Antinociceptive, antipyretic, Eddy’s Hot plate, Analgesiometer, Salix tetrasperma
Welcome to IJPBS,Pharmaceutics, Novel, drug, delivery, system, Nanotechnology, Pharmacology, Pharmacognosy
Pharmaceutical Fields
Welcome to IJPBS,Pharmaceutics, Novel, drug, delivery, system, Nanotechnology, Pharmacology, Pharmacognosy Pharmaceutics
Welcome to IJPBS,Pharmaceutics, Novel, drug, delivery, system, Nanotechnology, Pharmacology, Pharmacognosy Novel drug delivery system
Welcome to IJPBS,Pharmaceutics, Novel, drug, delivery, system, Nanotechnology, Pharmacology, Pharmacognosy Nanotechnology
Welcome to IJPBS,Pharmaceutics, Novel, drug, delivery, system, Nanotechnology, Pharmacology, Pharmacognosy Pharmacology
Welcome to IJPBS,Pharmaceutics, Novel, drug, delivery, system, Nanotechnology, Pharmacology, Pharmacognosy Pharmacognosy
© Copyright 2009-2015 IJPBS, India. All rights reserved. Specialized online journals by ubijournal. Website by Ubitech Solutions
         Home I Contact I Terms & Conditions