The antifungal drugs in common usage leads to failure in the treatment of mycosis due to the occurence of drug resistance. Hence, alternative natural anti-mycotic drugs are required which should be effective in the control of dermatophytosis in both animals and humans. The present study constitutes an initiative to explore the anti-dermatophytic potential of Cinnamomun tamala leaf essential oil against dermatophytes. Anti- dermatophytic activity against Microsporum audouinii and Trichophyton mentagrophytes were determined in terms of mycelial growth inhibition (MGI) and minimum inhibitory concentration (MIC). C. tamala essential oil showed lower values of MIC against both dermatophytes as compared to the standard antifungal chemicals. The essential oil also significantly inhibited the mycelial growth of both the fungi. Hence, C. tamala essential oil can be formulated into the antifungal ointments for topical applications in future.
Keywords: Dermatophytes, Indian bay leaf, Minimum Inhibitory Concentration, Mycelial Growth Inhibition, Mycosi