Boucerosia procumbens (Gravely & Mayur.) an endemic and endangered medicinal plant belonging to the family Apocynaceae was analyzed for antibacterial and antifungal activity. It was carried out with ethanol, aqueous, benzene, acetone and chloroform extracts.   The zone of inhibition possessed by various extracts was compared. The ethanol extract showed the highest inhibitory effect against the selected pathogenic microorganisms when compared with the control. The results proved that this plant can be used as an antimicrobial agent.