International Journal of Pharma and Bio Sciences
 
 
    ISSN 0975-6299
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RESEARCH ARTICLE
Int J Pharm Bio Sci Volume 7 Issue 3, 2016 (July-Sept), Pages:943 - 949
ANTIFUNGAL POTENTIAL OF CINNAMOMUM TAMALA (TEJPAT) LEAF ESSENTIAL OIL AGAINST CURVULARIA LUNATA, A DESTRUCIVE CELLULOLYTIC FUNGUS
NEERAJ SRIVASTAVA
DOI:
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Abstract:

Curvularia lunata (Wakker) Boedijn is a destructive cellulolytic fungus of Class – Hyphomycetes of Fungi Imperfecti. This mold fungus causes biodeterioration of our cultural heritage in paper manuscripts and books in libraries etc. Its occurrence has been reported from different libraries of the world and India, including Gorakhpur. Chemical fungicides used to control this fungus not only deface and destroy the objects, but are toxic, non-ecofriendly, non-biodegradable, highly pollutive and many of them have carcinogenic and other harmful effects too. Cinnamomum tamala T. Nees & C.H. Eberm. (Tejpat in Hindi), Family – Lauraceae contains volatile essential oils in its leaves having antimicrobial properties. In the present investigation, the fungitoxic efficacy of vapour of essential oil extracted from Cinnamomum tamala leaves has been tested against Curvularia lunata. Different parameters used to determine the antifungal potential of the oil in vitro are Minimum Inhibitory Concentration (MIC), Minimum Lethal Concentration (MLC) and inoculum density sustained at MIC and hyper MIC doses (fungicidal or fungistatic). It is concluded that this essential oil is effective against the test fungus – Curvularia lunata and can be recommended for further in vivo investigations. It is also suggested that Cinnamomum tamala leaf oil should be tested in vitro and in vivo against strains of Curvularia lunata causing Allergic Bronchopulmonary Diseases and Allergic Fungal Sinusitis in humans in order to explore the possibility of its use as a chemotherapeutic agent.

Keywords: Natural fungicide, Fungitoxic potential, Cinnamomum tamala (Tejpat), Essential oil, Curvularia lunat
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