International Journal of Pharma and Bio Sciences
 
 
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ORIGINAL RESEARCH ARTICLE
Int J Pharm Bio Sci Volume 2 Issue 1, 2011 (January - March), Pages:251-260

Synthesis, analgesic and ulcerogenic evaluation of some novel schiff and mannich bases of isatin derivatives

Ramachandran S.,Uma Maheswari V.
DOI:
Abstract:

Novel schiff and mannich bases of isatin derivatives were synthesized. The structures of these compounds were established by means of IR, 1H-NMR analysis. All the compounds were evaluated for analgesic and ulcerogenic activities. Most of the compounds shown significant analgesic activity and lesser ulcerogenic property, when compared with the standard drugs.  
 

Keywords: Isatin, Schiff and Mannich bases, Analgesic, Ulcerogenic.
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