International Journal of Pharma and Bio Sciences
ijpbs.net
editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com
10.22376/ijpbs.2019.10.1.p1-12
Volume 4 Issue 1
2013 (January - March)
QSAR STUDIES OF SOME PYRAZOLONES AS ANTIMICROBIAL AGENT
In the present study Quantitative Structure Activity Relationship (QSAR) studies were performed on selected pyrazolone compounds as antimicrobial agent. The compoundshas been established on the basis of analytical methods and advanced spectroscopic techniques. Three compounds lessThan i greaterThan viz lessThan /i greaterThan . 4-Amino antipyrine thiosemicarbazone (C-8), 1-(2-Chloro-5-sulfophenyl)-3-methyl-5-pyrazolone (C-9) and 1-(4-Sulfoamido phenyl)-3-methyl-5-pyrazolone (C-10) recorded significant antifungal activity against lessThan i greaterThan Macrophomina phaseolina. lessThan /i greaterThan
KISHOR ARORA AND VEENA NATHANI
Antimicrobial activity, Macrophomina phaseolina, Pyrazolones, QSAR
657-671