International Journal of Pharma and Bio Sciences
ijpbs.net
editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com
10.22376/ijpbs.2019.10.1.p1-12
Volume 4 Issue 2
2013 (April - June)
INHIBITORY EFFECT OF ESSENTIAL OILS ON EXTRACELLULAR LIPASE ACTIVITY OF MALASSEZIA GLOBOSA
lessThan i greaterThan Pityriasis capitis lessThan /i greaterThan is a common scalp disorder caused by a fungus lessThan i greaterThan Malassezia globosa lessThan /i greaterThan . The mechanism of lessThan i greaterThan Pityriasis capitis lessThan /i greaterThan includes lessThan i greaterThan Malassezia lessThan /i greaterThan -induced fatty acid metabolism, particularly lipase-mediated breakdown of sebaceous lipids and release of irritating free fatty acids. We report that extracellular lipase activity was detected in lessThan i greaterThan Malassezia globosa lessThan /i greaterThan . The presence of lipase enzyme was performed in specific media on Petri dishes for formation of a zone.In this article, the effect of lessThan i greaterThan Cymbopogon citratus lessThan /i greaterThan and lessThan i greaterThan Zingiber officinale lessThan /i greaterThan essential oils on the extracellular lipase activity of lessThan i greaterThan Malassezia globosa lessThan /i greaterThan had been studied by titrametric lessThan i greaterThan method lessThan /i greaterThan . At the end of titration 4 µmol fatty acid/ml of reaction mixture was released in the presence of lessThan i greaterThan Cymbopogon citratus lessThan /i greaterThan oil and 7µmol of fatty acid/ml of reaction mixture was liberated in the presence of lessThan i greaterThan Zingiber officinale lessThan /i greaterThan oil. It was found that both essential oils strongly inhibit the lipase activity of M. lessThan i greaterThan globosa lessThan /i greaterThan at a lower concentration.
SHUBHANGI MUGAL,RANJANA VERMA,RENU MISHRA AND SHIKHA MANDLOI.
Zingiber officinale, M. globosa, Cymbopogon citratus, lipases
22-28