International Journal of Pharma and Bio Sciences
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10.22376/ijpbs.2019.10.1.p1-12
Volume 4 Issue 2
2013 (April - June)
TO STUDY THE BACTERIOLOGICAL AND MYCOLOGICAL PROFILE OF CHRONIC SUPPURATIVE OTITIS MEDIA PATIENTS AND THEIR ANTIBIOTIC SENSITIVITY PATTERN
Chronic suppurative otitis media(CSOM) has been a source of a tremendous health predicament since time immemorial and even today it is immensely intricate. It is an important cause of hearing impairment which in turn may cause serious long term effect on language, auditory and cognitive development and on educational development.Knowledge of the prevailing flora and their susceptibility to antimicrobials will guide the clinician as to prescribing an empirical regimen so that a better and more specific management can be provided to the patients. Hence this study is done in present secenario to isolate the organims associated with CSOM and its susceptibility pattern. To identify the bacterial and fungal profile of Chronic Suppurative Otitis Media patients. 120 patients attending ENT OPD in Navodaya Medical College Hospital and Research Centre were analysed from Nov 2009 to Oct 2010. Using predefined inclusion and exclusion criteria, samples were obtained using sterile cotton microswabs. These were cultured for microbial flora and were identified . Drug susceptibility was done using Kirby Bauer disc diffusion method.The most common organism isolated was Pseudomonas aeruginosa 33% followed by Staphylococcus aureus 25.8% among the 91 bacterial isolates. This was followed by Proteus mirabilis 20.6%, Enterobacter aerogenes and Streptococcus spp at 4.1%. The organisms were most prevalant in winter and early spring between Nov- Feb. Also maximum number of cases were seen in age group of 21-30 years.The organisms were sensitive to gatifloxacin, cefoperazone sulbactum and ceftriaxone.Fungal isolates accounted for 6.2% of the organism with Aspergillus flavus 3.1%, Aspergillus niger 2.1% and Candida albicans 1%.The study suggests that Pseudomonas aeruginosa and Staphylococcus aureus are the most common etiological agents of CSOM. Most of the strainwere sensitive to fluoroquinolones and cephalosporins.
ASISH J , AMAR M, VINAY HAJARE, SREEKANTHA, AVINASH SS AND AMARESHAR M.
CSOM, Pseudomonas aeruginosa, Staphylococcus aureus, Antibiotics,Aspergillus flavus, Aspergillus niger, Candida albicans.
186-199