International Journal of Pharma and Bio Sciences
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editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com
10.22376/ijpbs.2019.10.1.p1-12
Volume 5 Issue 1
2014 (January - March)
SYNTHESIS AND ANTI BACTERIAL ACTIVITY OF 2-(4-AMINOPHENYL) BENZIMIDAZOLE BASED PYRAMIDINE DERIVATIVES
As a part of systematic investigation of synthesis ,characterization and biological activities of N-(4-(1H-benzo(d)imidazole -2-yl )-2-(4-hydroxy -6-methyl pyramidine -2-yl thio) acetamide have been synthesized from 2-(4-aminophenyl) benzimidazole and 2-mercapto -4-hydroxy -6-methyl pyramidine ,which have been prepared from p-amino benzoic acid and benzene 1,2 diamine and EAA with thiourea. All the synthesized compounds have been characterized by lessThan sup greaterThan 1 lessThan /sup greaterThan HNMR; IR spectral data .The prepared compounds were tested for antibacterial activity.
KUMARASWAMY GULLAPELLI, MURALI KRISHNA THUPURANI AND G.BRAHMESHWARI
Synthesis, benzimidazole, pyramidine, Antibacterial activity
682-690