International Journal of Pharma and Bio Sciences
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10.22376/ijpbs.2019.10.1.p1-12
Volume 6 Issue 1
2015 (January - March)
EVALUATION OF ANTIBACTERIAL PROPERTIES OF FRUIT PEEL EXTRACTS OF CITRUS KARNA AGAINST HUMAN PATHOGENS
The antibacterial activity of lessThan i greaterThan Citrus karna lessThan /i greaterThan fruit peel extracts was evaluated on bacteria strains like lessThan i greaterThan Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus lessThan /i greaterThan and lessThan i greaterThan Bacillus subtilis. lessThan /i greaterThan Hexane, chloroform and methanol were used for extraction and the antibacterial activity was performed by agar well diffusion method. The results were compared with ampicillin, a commercial antibacterial agent. Methanolic extract shows the highest antibacterial activity against all the four bacterial strains, whereas hexane extract shows lowest antibacterial activity. Among the tested bacterial isolates lessThan i greaterThan P. aeruginosa lessThan /i greaterThan was the most inhibited majorly with the methanol extract. The methanolic extract shows lowest (14mm) zone of inhibition against lessThan i greaterThan B. subtilis lessThan /i greaterThan . The chloroform extract displayed inhibitory zones of between 12-15mm while the hexane extract exhibited inhibitory affinity between 11-13mm. The MIC of the plant extracts on the susceptible bacterial isolates was between 37-333µg/ml. Present study concludes that fruit peels of lessThan i greaterThan Citrus karna lessThan /i greaterThan have a broad spectrum antibacterial activity against human pathogens.
SIKANDER DAR AND REENA S LAWRENCE
Citrus karna fruit peel extracts, Antibacterial activity, zone of inhibition, MIC
261-266