International Journal of Pharma and Bio Sciences
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10.22376/ijpbs.2019.10.1.p1-12
Volume 7 Issue 2
2016 (April - June)
EVALUATION OF ANTIMICROBIAL ACTIVITY OF THE DIFFERENT CULTURE EXTRACTS OF CYANOBACTERIAL SPECIES
The main aim of the present investigation was to assess the efficacy of the antimicrobial activity of lessThan i greaterThan Anabaena circinalis, Nostoc muscorum, Stigonema ocellatum lessThan /i greaterThan and lessThan i greaterThan Hapalosiphon welwitschii lessThan /i greaterThan . The antimicrobial activity of cyanobacterial species were screened by using Agar disc diffusion method against pathogenic bacteria and fungi. Chloroform extract of lessThan i greaterThan A. circinalis lessThan /i greaterThan was resulted the highest antibacterial activity 21.00 ± 0.57 mm against lessThan i greaterThan E. coli lessThan /i greaterThan followed by lessThan i greaterThan K. pneumonia. lessThan /i greaterThan Similarly, highest antifungal activity 15.00 ± 1.15 mm was recorded with lessThan i greaterThan N. muscorum lessThan /i greaterThan followed by lessThan i greaterThan S. ocellatum lessThan /i greaterThan and lessThan i greaterThan A. circinalis lessThan /i greaterThan against lessThan i greaterThan Trichophyton mentagrophytes lessThan /i greaterThan , lessThan i greaterThan Aspergillus fumigatus lessThan /i greaterThan and lessThan i greaterThan Aspergillus niger lessThan /i greaterThan respectively. Chloroform extract was showed highest antimicrobial activity among all the solvents tested; ethyl acetate and methanol were the next preferred solvents. Statistical analysis of the data showed a significant ( lessThan i greaterThan P lessThan /i greaterThan ≤0.05) difference between the different solvents, cyanobacterial species against bacteria and fungi tried. In conclusion the present investigation suggested that cyanobacteria used as a potential natural drug sources owing to the antimicrobial efficiency.
T. MALATHI, M. RAMESH BABU, D. SRINIVAS AND B. DIGAMBER RAO
Anabaena circinalis, Nostoc muscorum, Stigonema ocellatum, Hapalosiphon welwitschii, Agar disc diffusion technique, Antimicrobial activity
371-378