International Journal of Pharma and Bio Sciences
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10.22376/ijpbs.2019.10.1.p1-12
Volume 2 Issue 2
2011 (April - June)
Non-HDL Cholesterol And LDL-C/HDL-C Ratio In Type II Diabetic Patients
Diabetic dyslipidemia consists of elevated LDL cholesterol, Triglycerides and decreased levels of HDL Cholesterol. More recent data suggests that measurement of Non -HDL Cholesterol level (calculated as Total Cholesterol minus HDL Cholesterol) could be more representative of all atherogenic, apolipoprotein (apo) B containing lipoproteins. Although apolipoprotein B can be assessed directly, measurement of Non-HDL Cholesterol can be considered as a surrogate marker for apolipoprotein B in routine clinical practice. Here an attempt is to evaluate the Lipid profile including Non-HDL Cholesterol levels and LDL-C/HDL-C ratio in type II Diabetic Patients as markers of diabetic dyslipidemia. Our study group comprised of age and sex matched 50 normal, 50 type II diabetic subjects. There was a significant increase in Non-HDL cholesterol (p lessThan 0.001) and LDL-C/HDL-C ratio(P lessThan 0.05) in diabetic patients compared to age and sex matched controls. Hence Non-HDL Cholesterol along with LDL-C/HDL-C ratio can be used as markers of dyslipidemia in Type II Diabetic patients.
Indumati V., Vidya S. Patil, Krishnaswamy D., Satishkumar D., Vijay V., Mahesh S., And Rajeshwari V.
Atherogenic lipoproteins, Diabetic Dyslipidemia, LDL-C/HDL-C ratio, Non-HDL Cholesterol.
71-77