The importance of mouth and teeth cleanliness has been recognized from the earliest days of civilization to the 21st century. Patients and oral health practitioners are faced with a multitude of mouthwash products containing many different active and inactive ingredients. Making informed decisions as to the suitability of a particular product for a particular patient can be a complex task. Although many popular herbal products have helped to control dental plaque and gingivitis, they have been used for a short time and only as an adjunct to other oral hygiene measures such as brushing and flossing. Various herbal products and their extracts such as Guava, Pomegranate, Neem, Propolis, Tulsi, Green Tea, Cranberry, Grapefruit etc, have shown significant advantages over the chemical ones. Natural mouthwashes may offer significant advantages over the chemical ones. If such mouthwashes can be formulated which can be easily prepared and used safely by people at home using natural products, it may lead to improvement in the general dental health of the population. This review is an attempt to outline such natural substances, which may be used as effective mouthwashes.