International Journal of Pharma and Bio Sciences
    ISSN 0975-6299

Int J Pharm Bio Sci Volume 11 Issue 4, 2020 (October-December), Pages:154-161

Management of neonates born to coronavirus(covid-19) infected pregnant mother

Prof. Dr. P. Paramanantham

A new public health crises threatening world with the emergence and spread of 2019 novel coronavirus [2019 nCoV] or severe acute respiratory syndrome coronavirus 2 [SARS CoV-2]. The virus originated in bats and was transmitted to humans through yet unknown intermediary animals in Wuhan, Hubei province, China in December 2019. The disease is transmitted by inhalation or contact with infected droplets and the incubation period ranges from 2 to 14 d. The symptoms are usually fever, cough, sore throat, breathlessness, fatigue, malaise among others. The disease is mild in most people; in some [usually the elderly and those with comorbidities], it may progress to pneumonia, acute respiratory distress syndrome [ARDS] and multi organ dysfunction. Many people are asymptomatic. The case fatality rate is estimated to range from 2 to 3%. Diagnosis is by demonstration of the virus in respiratory secretions by special molecular tests. Common laboratory findings include, normal/ low white cell counts with elevated C- reactive protein[CRP]. The computerized tomographic chest scan is usually abnormal even in those with no symptoms or mild disease. The virus spreads faster than its two ancestors the SARS-CoV and Middle east respiratory syndrome coronavirus [MERS-CoV], but has lower fatality. The purpose of this review is to summarize, the available evidence on human corona virus, transmission, clinical presentation, lab investigation, diagnosis and management of new born to provide adequate information, SARS-CoV2 transmission, clinical presentation, outcomes and treatment of newborn infants to provide adequate information regarding breast feeding to neonatologists, isolation of neonates to pediatricians and obstetricians for managing such neonates and mother.

Keywords: Perinatal COVID, Neonatal COVID, COVID-19, Coronavirus, COVID-19 impact, Social impact.
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