International Journal of Pharma and Bio Sciences
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10.22376/ijpbs.2019.10.1.p1-12
Volume 1 Issue 4
2010 (October - December)
New Analytical Methods For The Estimation Of Racecadotril In Bulk And Pharmaceutical Formulations
Three simple and sensitive visible spectrophotometric methods (A-C) for the determination of Racecadotril in bulk and pharmaceutical formulations are described. They are based on the formation of colored species by treating with Folin-Ciocalteau (F.C) reagent under alkaline conditions (Method A, λmax: 742 nm) or 1, 10-phenanthroline (PTL) in the presence of ferric chloride (Method B, λmax: 510 nm) or 2, 2, -Bipyridine (BPN) in the presence of ferric chloride (Method C, λmax : 520 nm). These methods were extended to the analysis of pharmaceutical preparations and the results are compared with the reference method (USP).
E. Venumadhav,Amreen Nishat,T. Neeha,P. Bhargavi,A. Swetha,G. Devala Rao
Spectrophotometry, Racecadotril, Pharmaceutical preparations.
348-351