<?xml version="1.0" encoding="utf-8"?>
<Journal>
<Journal-Info>
<name>International Journal of Pharma and Bio Sciences</name>
<website>ijpbs.net</website>
<email>editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com</email>
</Journal-Info>
<article>
<article-id pub-id-type='other'>10.22376/ijpbs.2019.10.1.p1-12</article-id>
<issue_number>Volume 1 Issue 4</issue_number>
<issue_period>2010 (October - December)</issue_period>
<title>Estimation Of Trace Amounts Of Chromium (III) In Various Multi-Vitamin Pharmaceutical Formulations</title>
<abstract>New specific, selective, simple &amp; inexpensive spectroscopic method for estimating a trace amount of chromium (Cr lessThan sup greaterThan +3 lessThan /sup greaterThan ) from pharmaceutical formations was developed. The proposed method is based on the conversion of Cr lessThan sup greaterThan +3 lessThan /sup greaterThan  to Cr lessThan sup greaterThan +6  lessThan /sup greaterThan  by oxidation with a sodium hydroxide-hydrogen peroxide followed by the complexation of Cr lessThan sup greaterThan +6 lessThan /sup greaterThan  with 1.5 diphenylcarbazide (DPC) in a mineral acidic solution of pH 1.0±0.5. The pink-colored complex was estimated at 540 nm.The advantage of method is that it does not required preashing of the sample as it shown in the various method. Method was found to be linear in the range of 1-9 µg/ml. with a limit of detection is 0.166µg/ml and a limit of quantitation is 0.555 µg/ml. Method was found to be suitable for estimating Cr lessThan sup greaterThan +3 lessThan /sup greaterThan  species in various formulations. Satisfactory recovery from spiked samples of standard Cr lessThan sup greaterThan +3 lessThan /sup greaterThan  suggests no interference of any excipiants and diverse ions present in a formulation. </abstract>
<authors>Nisha H. Parikh,Rajashree C. Mashru</authors>
<keywords>Chromium, Multi vitamin formulation </keywords>
<pages>388-394</pages>
</article>
</Journal>
