10.22376/ijpbs.2019.10.1.p1-12 Volume 3 Issue 2 2012 (April - June) The lessThan i greaterThan in vitro lessThan /i greaterThan antifungal activities of few novel 4-aminoantipyrine derived Schiff bases and their metal complexes were tested against fungi such as lessThan i greaterThan Aspergillus niger, Fusarium solani, Culvularia lunata, Rhizoctonia bataicola lessThan /i greaterThan and lessThan i greaterThan Candida albicans lessThan /i greaterThan . All the metal complexes showed stronger antifungal activities than the free ligands. The synthesized compounds were subjected to molecular docking studies for the inhibition of the enzyme glucosamine-6-phosphate synthase which is a new target for antifungals S.Sobha And N.Raman Antifungal agents, Schiff base, 4-aminoantipyrine, Transition metal complexes 116-123