10.22376/ijpbs.2019.10.1.p1-12 Volume 3 Issue 2 2012 (April - June) The effect of daily oral administration of flumethrin on the tissue enzyme activity on albino rats was investigated. In the present study twenty albino Wister rats were used and divided into two groups. The first group (10 rats) served as the control group; the second group (10 rats) both male and female received flumethrin (1% pour on formulation) at the rate of 5 mg/kg bw orally daily for 14 days. On day 15, animals were sacrificed and liver tissue samples were collected. Flumethrin leads to increased MDA, ALT, AST levels and decreased catalase, SOD and protein level. The present study suggests that flumethrin is having hepato-toxic effect, producing oxidative stress in animal's body. Akhilesh Mishra*, Gayatri Dewangan, Vikas Mahajan And T K Mandal1 Flumethrin; oxidative stress; superoxide dismutase; lipid peroxidation; aspartate transaminase; alanine transaminase 191-200