International Journal of Pharma and Bio Sciences
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10.22376/ijpbs.2019.10.1.p1-12
Volume 3 Issue 3
2012 (July - September)
Evaluation Of Diuretic Effect Of Ethanolic Seed Extracts Of Macrotyloma Uniflorum And Cucumis Melo In Rats
The present study was undertaken to investigate the diuretic effect of ethanolic seed extracts of lessThan i greaterThan Macrotyloma uniflorum lessThan /i greaterThan and lessThan i greaterThan Cucumis melo lessThan /i greaterThan in Albino rats. Ethanolic extracts of the seeds were administered to experimental rats orally at doses of 200mg/kg and 400mg/kg each p.o. Furosemide (5mg/kg) was used as a standard. The diuretic effects of the extracts were evaluated by measuring the Urine volume, Sodium, Potassium, Chloride and Bicarbonate contents. A significant Diuretic effect was observed from the experimental animals treated with extracts of lessThan i greaterThan Macrotyloma uniflorum lessThan /i greaterThan and lessThan i greaterThan Cucumis melo lessThan /i greaterThan individually compared to the control. Further, extract of lessThan i greaterThan Cucumis melo lessThan /i greaterThan (400mg/kg) showed more diuretic effect than standard. This might be the first formal report on diuretic effects of both extracts individually. The results, to some extent explains the use of lessThan i greaterThan Macrotyloma uniflorum and Cucumis lessThan /i greaterThan lessThan i greaterThan melo lessThan /i greaterThan as a cure for renal diseases in Indian traditional medical practice. lessThan sup greaterThan 1 lessThan /sup greaterThan
K.Ravishankar And P.S.V.Vishnu Priya
Diuretic activity, Macrotyloma uniflorum, Cucumis melo, Albino rats, natriuretic, Saluretic effect.
251-255