10.22376/ijpbs.2019.10.1.p1-12 Volume 3 Issue 4 2012(October - December) In the present study of chloroform extract of leaves of lessThan i greaterThan Flaveria trinervia lessThan /i greaterThan (Sprengel) C.Mohr. (Asteraceae) obtained by soxhlet extraction method was tested for anti-inflammatory activity by carrageenan induced paw edema in rats. The chloroform extract in dose of 250mg /kg b.w was administered orally.Anti- inflammatory activity effect was compared with standard drug – Indomethacin (10mg/kg b.w) showed 31% and 51% inhibition of paw edema, in extract and standard respectively. These observations help us to conclude that chloroform extract has showed good anti- inflammatory activity against carrageenan induced paw edema. M. MALATHI, M .S. SUDARSHANA AND M. H. NIRANJAN Flaveria trinervia, Anti- inflammatory, Carrageenan, Indomethacin, Plethysmograph. 218-221