10.22376/ijpbs.2019.10.1.p1-12 Volume 3 Issue 4 2012(October - December) The Cu(II), Co(II), Ni(II), Zn(II), Cd(II) and Hg(II) complexes of the Schiff base derived from reaction between benzofuran-2-carbohydrazide and acetophenone have been synthesized. The synthesized complexes have been characterized on the basis of elemental analysis, conductivity data, magnetic properties, IR and lessThan sup greaterThan 1 lessThan /sup greaterThan H NMR spectral studies. The spectral study shows that Schiff base act as bidentate by coordinating through the azomethine nitrogen and oxygen of the carbonyl groups. Based on these results we have proposed the tentative structure for all of these complexes. The antifungal and antibacterial activities of the ligand and their metal complexes have been screened against fungi lessThan i greaterThan Aspergillus niger lessThan /i greaterThan and lessThan i greaterThan Candida albicans lessThan /i greaterThan and against bacteria lessThan i greaterThan Escherichia coli lessThan /i greaterThan and lessThan i greaterThan Staphylococcus aureus. lessThan /i greaterThan M. B. HALLI, RAVINDRA. S. MALIPATIL AND R. B. SUMATHI Schiff’s base, Metal complexes, Spectral studies, Antimicrobial activity. 547-557