10.22376/ijpbs.2019.10.1.p1-12 Volume 3 Issue 4 2012(October - December) A novel flavonoidic compound, 3,5-dihydroxy-4',7-dimethoxyflavone, has been isolated from the rhizomes of lessThan i greaterThan Zingiber phillipseae lessThan /i greaterThan . The dichloromethane extract of this species was shown to be non-toxic with LC lessThan sub greaterThan 50 lessThan /sub greaterThan for acute and toxic levels at 9,732 ppm and 562 ppm, respectively. The extract showed higher antioxidant activity than the standard (butylated hydroxytoluene, BHT) but lower than dichloromethane extract of lessThan i greaterThan Zingiber officinale lessThan /i greaterThan . It showed significant activity against lessThan i greaterThan Staphylococcus aureus lessThan /i greaterThan and lessThan i greaterThan Escherichia coli lessThan /i greaterThan with minimum inhibitory concentration (MIC) at 200µg/ml and 225 µg/ml respectively. Both extracts were found negative toward lessThan i greaterThan Candida albicans lessThan /i greaterThan . TAN WEI HSIANG AND MASHITAH M. YUSOFF Zingiber phillipseae; 3,5-dihydroxy-4’,7-dimethoxyflavone; brine shrimp test; antioxidant activity; antimicrobial activity 631-637