10.22376/ijpbs.2019.10.1.p1-12 Volume 3 Issue 4 2012(October - December) lessThan i greaterThan Bacopa monnieri L lessThan /i greaterThan plants raised through micropropagation were evaluated for the production of major secondary metabolite, 'Bacoside-A' and its pharmacological properties in comparison to the conventional source i.e. , natural ( lessThan i greaterThan in vivo lessThan /i greaterThan ) plants. The hepatoprotective function of the ethanolic extract containing Bacoside-A of lessThan i greaterThan in vitro lessThan /i greaterThan grown lessThan i greaterThan B. mannieri lessThan /i greaterThan was evaluated in carbon tetrachloride (CCl lessThan sub greaterThan 4 lessThan /sub greaterThan ) - intoxicated albino mice. Analysis of ethanolic extract of lessThan i greaterThan in vitro lessThan /i greaterThan raised Bacopa plants by HPTLC confirmed presence of Bacoside-A identical to that of seed borne Bacopa. Administration of lessThan i greaterThan Bacopa lessThan /i greaterThan ethanolic extract from either source ( lessThan i greaterThan in vitro lessThan /i greaterThan or natural) markedly prevented CCl lessThan sub greaterThan 4 lessThan /sub greaterThan -induced hepatic damage in albino mice model as indicated by the levels of serum markers (SGPT, SGOT and Bilirubin) of hepatic damage. The present study confirmed that lessThan i greaterThan in vitro lessThan /i greaterThan generated lessThan i greaterThan Bacopa monnieri lessThan /i greaterThan produces 'Bacoside-A' with pharmacological function identical to that generated from natural plantlet. Thus, lessThan i greaterThan in vitro Bacopa lessThan /i greaterThan cultures serve as efficient alternate source of 'Bacoside-A' for pharmacological use. TEJOVATHI GUDIPATI , PRATIMA SRIVASTAVA, REKHA BHADAURIA AND G.B.K.S. PRASAD SGPT, SGOT, Bacopa, Bacoside-A, Hepatotoxicity, Bilirubin, CCl4 664-672