10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 1 2013 (January - March) 2-Styrylchromones are very good biological active compounds, prepared by Baker-Venkataraman rearrangement through 1,3-diketones as intermediates starting from lessThan i greaterThan o lessThan /i greaterThan -hydroxyacetophenones and cinnamic acids. The synthesized compounds are characterized by some physical properties and spectral studies like IR, NMR and LCMS. They are screened for their antimicrobial activity against lessThan i greaterThan Xanthomonas campestis lessThan /i greaterThan & lessThan i greaterThan Agrobacterium lessThan /i greaterThan lessThan i greaterThan tumafeciens lessThan /i greaterThan bacteria and lessThan i greaterThan Aspergillus niger lessThan /i greaterThan & lessThan i greaterThan Penicillum chrysogenium lessThan /i greaterThan fungal strains. Among five synthetic compounds, chloro and methoxy substituted compounds exhibit very good activity. B. UJWALA, P. PRIYADARSINI, AND V. MADHAVA RAO 2-Styrylchromones, 1,3-diketones, antimicrobial activity, Xanthomonas campestris, Aspergillus niger etc. 199-206