10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 1 2013 (January - March) Acidic phospholipase A lessThan sub greaterThan 2 lessThan /sub greaterThan (NND-IV-PLA lessThan sub greaterThan 2 lessThan /sub greaterThan ) was isolated from lessThan i greaterThan NajaNaja lessThan /i greaterThan (Southern India) venom, was purified by anion and cation exchange chromatography. The acidic PLA lessThan sub greaterThan 2 lessThan /sub greaterThan profile of eastern and southern region venom is distinctly different from that of the western regional venom, Southern regional acidic phospholipase A lessThan sub greaterThan 2 lessThan /sub greaterThan did not inducemyotoxicity or anticoagulant activity and didn't induced edema. However, the acidic PLA lessThan sub greaterThan 2 lessThan /sub greaterThan from all the regions follow the pattern of increasing catalytic activity with increase in the acidic nature of the PLA lessThan sub greaterThan 2 lessThan /sub greaterThan isoforms. DAYANANDA.K.S, VISHWANATH B.S, SHARATH B.K AND GOPINATH S.M Acidic phospholipase A2,Hemolytic activity, Edema, Myotoxicity, LD50, Anticoagulant activity. 408-415