10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 1 2013 (January - March) Dengue fever is an arboviral infection with the largest incidence worldwide, transmitted by lessThan i greaterThan Aedes aegypti lessThan /i greaterThan . The aim of the study is to study the role of serum transaminases on dengue fever. The serum glutamic oxaloacetic transaminases (SGOT) and serum glutamic pyruvic transaminases (SGPT) were estimated by enzymatic (kinetic) methods for 50 dengue positive cases. Overall, 80% of dengue fever cases of this study showed increased values of serum transaminases. This study suggested that most of the dengue fever cases had elevated serum transaminases reflecting early liver damage. Early alterations of biochemical markers can predict dengue fever in patients with acute fever caused by dengue. SUMATHI K, MANJULADEVI A J, LAKSHMI K AND MENEZES GA Dengue fever, aspartate aminotransferase, alanine aminotransferase, hepatotoxicity. 429-433