10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 1 2013 (January - March) The aim of the present study was to investigate the effects of lessThan i greaterThan Mangifera indica lessThan /i greaterThan leaves extract on the kidney function parameters in alloxan induced diabetic Swiss albino mice. Forty five albino mice (weighing 28 to 32 g) were randomly divided into control, alloxan treated and lessThan i greaterThan Mangifera indica lessThan /i greaterThan treated mice group. Diabetes was induced in mice by injecting intraperitoneally alloxan monohydrate at dose of 150 mg/kg body weight. Ethanolic extracts of lessThan i greaterThan Mangifera indica lessThan /i greaterThan leaves at dose of 80 mg/kg body weight were given orally in diabetic mice daily for four weeks after established LD lessThan sub greaterThan 50 lessThan /sub greaterThan value. Results and discussion: In diabetic mice, serum urea, uric acid, creatinine and glucose levels were significantly increased but level of serum albumin was decreased in comparison with the control group. Diabetic mice group lessThan b greaterThan , lessThan /b greaterThan treated with ethanolic extract of lessThan i greaterThan Mangifera indica lessThan /i greaterThan leaves (80 mg/kg b.w) lessThan b greaterThan , lessThan /b greaterThan on comparison with diabetic group showed a significant decrease in these biochemical parameters such as urea, uric acid creatinine and glucose level. However, the serum albumin level got increased as compared to diabetic mice. The results suggested that ethanolic extract of lessThan i greaterThan Mangifera indica lessThan /i greaterThan leaves possesses protective effect against alloxan induced diabetic mice. BHASKAR SHARMA, MOHAMMAD SUHAIL, SHIV SHANKER KUMAR AND ARUN KUMAR Alloxanized Diabetes, Urea, Uric acid, Creatinine and Albumin 809-818