10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 1 2013 (January - March) Emergence of drug resistance amongst clinical isolates of bacteria and fungi has led to the need of search for alternate drug candidates. Medicinal plants are a source of antimicrobial agents and some of which have been used for centuries by tribes in Assam. In this study, extracts of six medicinal plants namely lessThan i greaterThan Cissus quadrangularis lessThan /i greaterThan L., lessThan i greaterThan Moringa oleifera lessThan /i greaterThan L., Z lessThan i greaterThan iziphus jujuba lessThan /i greaterThan M., lessThan i greaterThan Cassia fistula lessThan /i greaterThan L., lessThan i greaterThan Dillenia indica lessThan /i greaterThan L., and lessThan i greaterThan Paederia foetida L. lessThan /i greaterThan were tested for activity against clinical isolates of bacteria and fungi. The preliminary phytochemical analysis of the extracts was tested for the presence of alkaloids, glycosides, steroids, terpenoids, carbohydrates, amino acids and saponins. The extracts were subjected to screening of lessThan i greaterThan in vitro lessThan /i greaterThan antibacterial and antifungal activity against selected clinical isolates viz. lessThan i greaterThan Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Klebsiella pneumoniae, lessThan /i greaterThan lessThan i greaterThan Candida albicans lessThan /i greaterThan and lessThan i greaterThan Candida trophicalis. lessThan /i greaterThan All the extracts exhibited inhibitory activity against the test pathogens. For positive control, a standard disc containing antibiotic drug Amoxicillin (10µg/disc), Kanamycin (30µg/disc) and Ketoconazole (50µg/disc) was used. KANDARPA KR. SAIKIA Ph. D., VEDANT V BORAH M. Sc., M C KALITA Ph. D. AND MANGALA LAHKAR M. D. Antibacterial, Antifungal, Phytochemicals, Ayurveda 890-898