10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 3 2013 (July - September) This study examined the antinociceptive and antiinflammatory activities of the stem bark of the traditional medicinal plant, lessThan i greaterThan Hildegardia poulifolia lessThan /i greaterThan (Sterculiaceae), an endangered species lessThan i greaterThan . lessThan /i greaterThan  Methanolic bark extract of this species was investigated for the antinociceptive effect by using acetic acid-induced writhing and hot plate methods in albino mice and antiinflammatory activity by carrageenan, formalin and histamine induced paw edema in rats. The dose level at 200mg/kg body weight of test extract of lessThan i greaterThan H. populifolia lessThan /i greaterThan showed significantly better antinociceptive and antiinflammatory activities. The experimental data demonstrated that methanol extract of stem bark of lessThan i greaterThan H. populifolia lessThan /i greaterThan possess remarkable antinociceptive and antiinflammatory activities. Hence, the bark of this species may be a potential bioresource for the manufacturing the drugs of antiinflammatory property. SARADHA M AND S PAULSAMY antinociceptive, antiinflammatory activity, Hildegardia populifolia. 30-36