10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 3 2013 (July - September) Diabetes mellitus is a multifunctional disorder in which free radicals may cause oxidative cellular injury and changes in the activity of the antioxidant enzymes. So the objective of the study was to find out the antioxidant properties of lessThan i greaterThan Aloe vera lessThan /i greaterThan . Streptozotocin induced diabetic rats were treated with lessThan i greaterThan Aloe vera lessThan /i greaterThan extract (150 mg and 300 mg/kg) and standard drug Vit C (9 mg/kg) in different groups. The normal rats were treated with distilled water and same doses of lessThan i greaterThan Aloe vera lessThan /i greaterThan . The antioxidant parameters like plasma superoxide dismutase, plasma malonaldehyde (MDA) and liver glutathione (GSH) was estimated after 21 days of treatment. lessThan i greaterThan Aloe vera lessThan /i greaterThan in both the doses (150 and 300 mg/kg) increased the enzymatic antioxidants (SOD and GSH) and decreased the lipid peroxide (MDA) as compared to diabetic control (p lessThan 0.001). lessThan i greaterThan Aloe vera lessThan /i greaterThan has significant antioxidant properties which can be useful in diabetes. SATYAJIT MOHAPATRA, SUPRIYA PRADHAN, BANDANA RATH AND SASWATI TRIPATHY Diabetes mellitus, Aloe vera, Superoxide dismutase, Glutathione peroxidase 187-191