10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 3 2013 (July - September) The country-wide shortage of medical teachers in several pre- and para-clinical disciplines, calls for development of 'stand-alone' teaching modules which can replace them, wherever at all possible: our Microbiology department put together audio-visual power-point slides for one module of topics. These "teacher-less" classes were conducted for a batch of undergraduate students, in a case-control randomized format of study. Results of their attitude (qualitative) and performance scores (quantitative) were tabulated and analyzed and are presented here. Comparative literature is also discussed. S.FATIMA AND V.LEELA computer-based instruction, microbiology theory module, audio-visual class, microbiology teaching, educational intervention 111-116