10.22376/ijpbs.2019.10.1.p1-12 Volume 1 Issue 4 2010 (October - December) Smoking is established cardiovascular disease risk factor. But the mechanism how it cause cardiovascular risk is still not properly understood. This study was aimed to evaluate lipid and vitamin C metabolism in chronic smokers from central Bihar, India for public enlightment. 60 male cigarette smokers and 20 male non-smokers were enrolled. It was found that mean serum Triglycerides (TG), Total cholesterol (TC), Low density lipoprotein cholesterol (LDL-C), Very low density lipoprotein cholesterol (VLDL-C) and urinary vitamin C were significantly higher in smokers as compared to non-smokers. Mean serum High density lipoprotein cholesterol (HDL-C) was significantly lower in smokers as compared to non-smokers. All these adverse effects may lead to serious metabolic diseases like atherosclerosis Kshitish Kumar Kshitiz,Ram Binay Sinha, Jayashree Bhattacharjee Smoking, Lipid profile, coronary Heart Disease, Cholesterol, vitamin C. 106-113