10.22376/ijpbs.2019.10.1.p1-12 Volume 4 Issue 4 2013 (October - December) The production of extended-spectrum- β lactamases (ESBLs) is an important mechanism for resistance to the cephalosporins. The proper dectection of this enzyme is important for optimal patient care lessThan b greaterThan . lessThan /b greaterThan The aim of this study is to determine the prevalence and the antibiotic sensitivity pattern of ESBL producing gram negative bacilli lessThan b greaterThan . lessThan /b greaterThan All the urinary isolates were collected from patient suffering from urinary tract infections were tested for ESBL production by using both the double- disk approximation and the combination disk methods. Among the 218 strains collected from clinically diagnosed UTIs patient 144(66%) were ESBL producers including E.coli – 94(43%) Klebsiella spp – 24(11%), Pseudomonos aeroginosa – 14(0.6%), Citrobacter spp – 4(0.18%), Enterobacter spp – 6(0.27%), PRABHAKAR C MAILAPUR,DEEPA S AND ABHISEK ROUTRAY. ESBL producing gram negative bacilli.urinary tract infections 359-363