International Journal of Pharma and Bio Sciences
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10.22376/ijpbs.2019.10.1.p1-12
Volume 5 Issue 1
2014 (January - March)
ANTIMICROBIAL SENSITIVITY PATTERN OF PSEUDOMONAS AERUGINOSA ISOLATED FROM SPUTUM AND ISSUES RELATED TO THE RATIONALSELECTION OF ANTIMICROBIALS
Antimicrobial resistance is not only increasing the healthcare costs but also the severity and death rates from certain infections that could have been avoided by rational use of the existing and newer antimicrobial agents.. The present study is undertaken to prepare local antibiogram of lessThan i greaterThan Pseudomonas aeruginosa lessThan /i greaterThan isolated from sputum and to discuss general issues related to antimicrobials use.Total 310 sputum samples were collected and tested bacteriologically using standard procedures. Culture positivity of urine samples was found to be 66.7 %. The most common pathogens were lessThan i greaterThan K. pneumoniae lessThan /i greaterThan (40.2 %) followed by lessThan i greaterThan Pseudomonas aeruginosa lessThan /i greaterThan (28.3%), lessThan i greaterThan E. coli lessThan /i greaterThan (14.1%), lessThan i greaterThan Staphylococ ci lessThan /i greaterThan (12.5%) and others (4.9 %). Antimicrobial susceptibility testing was done by disk diffusion method described by Kirby-Bauer (1961). lessThan i greaterThan Pseudomonas aeruginosa lessThan /i greaterThan is most sensitive for gatifloxacin, cefoperazone, amikacin, cefipime, ceftazidime, norfloxacin, ciprofloxacin and ofloxacin.Considering the antibiotic susceptibility testing, cost, side effects and many other factors, gatifloxacin should be preferred for lessThan i greaterThan Pseudomonas aeruginosa lessThan /i greaterThan infection for RTI.
ASATI RAKESH KUMAR
Respiratory tract infection, sputum, Pseudomonas aeruginosa, antibiotic susceptibility testing, antimicrobial resistance, rational selection of antimicrobials.
754-761