10.22376/ijpbs.2019.10.1.p1-12 Volume 5 Issue 2 2014 (April - June) New ion – associate complexes of tadalafil hydrochloride with [ Cadmium (II) and Zinc (II)] thiocyanates were precipitated and the excess unreacted metal complex was determined. A new method was given for the determination of tadalafil drug in pure solutions, in pharmaceutical formulations and urine samples of diabetic patients type – II using atomic emission and atomic absorption spectrometry. The drug can be determined by the affort method in the range 0.32 - 160.65 μg mL lessThan sup greaterThan -1 lessThan /sup greaterThan . SABRY KH. MOHAMED, YOUSRI M. HUSSEIN AND BASSEM M. RAAFAT Atomic emission, atomic absorption, ion-associate complexes, pharmaceutical analysis. 285-291