10.22376/ijpbs.2019.10.1.p1-12 Volume 6 Issue 1 2015 (January - March) Red galangal ( lessThan i greaterThan Alpinia galanga lessThan /i greaterThan (L) Willd lessThan b greaterThan ) lessThan /b greaterThan is an aromatic plant which has potential as aromatherapy. The aim of this research was to evaluate and identify the red galangal essential oil as slimming aromatherapy through lessThan i greaterThan in vivo lessThan /i greaterThan observation in adult male lessThan i greaterThan Sprague Dawley lessThan /i greaterThan rats. The oil was separated by distillation and fractionated by silica gel column chromatography resulting five fractions. Crude essential oil, fractions 1 and 2 were further analyzed by gas chromatography-mass spectrometry and performed lessThan i greaterThan in vivo lessThan /i greaterThan assay. The major compounds in the crude oil were β-bisabolene (11.78%) and trans-caryophyllene (9.10%); in fraction 1 was bicyclo-2-heptene (12.08%); and pentadecane (11.09%) in fraction 2. After five weeks of inhalation with 0.1% concentration, body weight showed significant difference (P lessThan 0.05) and animals inhaling the crude oil had the lowest body weight compared to fraction 1 but not different compared to control and fraction 2 treated animals. In conclusion, red galangal's essential oil compound β-bisabolene and trans-caryophyllene were suggested as the responsible compounds that has slimming aromatherapy effect. RIZKI DAMAYANTI, IRMANIDA BATUBARA AND IRMA HERAWATI SUPARTO aromatherapy, slimming, red galangal, essential oil 283-289