10.22376/ijpbs.2019.10.1.p1-12 Volume 6 Issue 1 2015 (January - March) The polyphenol rich extracts of leaves of lessThan i greaterThan P.guajava lessThan /i greaterThan were evaluated for chemoprofiling and HPLC with respect to standard quercetin. With the HPLC it was calculated that 0.02% quercetin was present in total extracts. After that the complexation with phospholipids was carried out to convert the polyphenols of extracts of leaves of lessThan i greaterThan P.guajava lessThan /i greaterThan into their bio-absorbable lipophilic fraction which improve their pharmacokinetic profile. The activities were evaluated by lipid peroxidation inhibitory activity and anti-inflammatory activity using various lessThan i greaterThan in-vitro lessThan /i greaterThan and lessThan i greaterThan in-vivo lessThan /i greaterThan model. The superiority of the action of complexes has demonstrated the concepts behind the product development of the herbal raw material. In sum the synergism of the bio activity profile of phyto-constituents is possible by their complexation with phospholipids. TARUN KUMAR DASGUPTA , PRISCILLA M D’MELLO AND DEEP BHATACHRYA Anti-inflammatory, HPLC, phospholipid complex, anti-oxidant, bio-enhancement. 437-448