10.22376/ijpbs.2019.10.1.p1-12 Volume 1 Issue 2 2010 (April - June) A fast and reliable high performance liquid chromatography method for determination of paracetamol, chlorzaxozone and diclofenac potassium has been developed. The chromatographic method was standardised using a reverse phase C18 column with UV-VIS detector at 254 nm. Mobile phase consisted of methanol 0.01M monobasic sodium phosphate with equal volume of 0.01M ortho phosphoric acid (70:30) (pH adjusted to 2.5 ± 0.2 using 10% orthophosphoric acid) at a flow rate 1 ml/min. The method was validated and produced accurate and precise result for these drugs Angshuman Biswas,Arindam Basu Paracetamol, Chlorzoxazone, diclofenac potassium -