10.22376/ijpbs.2019.10.1.p1-12 Volume 6 Issue 1 2015 (January - March) In the present study the immune response level and various immunological properties in experimental mice was assessed after administering various extracts of lessThan i greaterThan A. nilotica lessThan /i greaterThan and immunosuppressive drugs. The ethanol extract of lessThan i greaterThan A. nilotica lessThan /i greaterThan showed highest antibody titre (7 log lessThan sub greaterThan 2 lessThan /sub greaterThan lessThan sup greaterThan 2 lessThan /sup greaterThan ) followed by hexane and chloroform extract (6 log lessThan sub greaterThan 2 lessThan /sub greaterThan lessThan sup greaterThan 2 lessThan /sup greaterThan ) and butanol and water extract (5.5 log lessThan sub greaterThan 2 lessThan /sub greaterThan lessThan sup greaterThan 2 lessThan /sup greaterThan ). The increment in 'B' lymphocyte number was much pronounced in mice by the administration of lessThan i greaterThan A. nilotica lessThan /i greaterThan in combination with immunoenhansive drug than the lone effect of immunoenhansive drug. B cell decrement was pronounced in mice treated with immunosuppressive drug while a moderate decrement was noticed due to lessThan i greaterThan A. nilotica lessThan /i greaterThan in combination with immunosuppressive drug. The increment in blood cell counts was much pronounced in mice by the administration of lessThan i greaterThan A. nilotica lessThan /i greaterThan in combination with immunoenhansive drug than the lone effect of immunoenhansive drug. The increment in 'T' cell count may be due to the impact of plant drug on the synthesis, proliferation and activation of 'T' cells in treated animals. G. HEMAMALINI AND P. NIRMALA Mice, immunomodulation, T-cell, B-cell and A.nilotica 846-853