10.22376/ijpbs.2019.10.1.p1-12 Volume 6 Issue 1 2015 (January - March) The best way to control mosquito borne diseases is to control the mosquito population. The present study was executed to evaluate the mosquito larvicidal activity of lessThan i greaterThan Nicotiana plumbaginifolia lessThan /i greaterThan leaves against malarial vector lessThan i greaterThan Anopheles stephensi. lessThan /i greaterThan Crude extracts and three different solvent extracts were bio-assayed against lessThan i greaterThan An. stephensi lessThan /i greaterThan larvae. LC lessThan sub greaterThan 50 lessThan /sub greaterThan and LC lessThan sub greaterThan 90 lessThan /sub greaterThan values were determined appropriately. Qualitative phytochemical tests were also done. Statistical justifications were drawn through Log-probit, regression and ANOVA analyses. Effects of bio-active fractions on some of the non-target water fauna were also examined. Crude extract was considerably mosquito larvicidal. Only ethyl acetate extractives exhibited larvicidal activity amongst all solvent extractives. Cent percent mortality of 1 lessThan sup greaterThan st lessThan /sup greaterThan , 2 lessThan sup greaterThan nd lessThan /sup greaterThan and 3 lessThan sup greaterThan rd lessThan /sup greaterThan instars larvae was noticed within 72 h at 50 ppm concentration. Leaves contained tannins, steroids and flavonoids. Non-target organisms were non-responsive to bioactive fractions. lessThan i greaterThan N. plumbaginifolia lessThan /i greaterThan leaves bear the potentiality to control lessThan i greaterThan An. stephensi lessThan /i greaterThan larvae in a target specific way. ANIKET SINGH, KUNTAL BHATTACHARYA AND GOUTAM CHANDRA Anopheles stephensi, Nicotiana plumbaginifolia, larvicide, Non-target organism, Phytochemicals 860-868