10.22376/ijpbs.2019.10.1.p1-12 Volume 6 Issue 1 2015 (January - March) Secondary metabolites of plant extracts are effective to maintain the health status of the living organisms, mainly on the digestive system of animals. lessThan i greaterThan Coccinia grandis lessThan /i greaterThan is a source of nutrient with abundance of effective microorganisms to digest the consumed foods on one hand and improve the health status of consumer on the other hand. With this background in the present study effectiveness of various organic solvent extracts of lessThan i greaterThan C.grandis lessThan /i greaterThan on the intestinal microbial population was screened. Among the various extracts of lessThan i greaterThan Coccinia grandis lessThan /i greaterThan studied ethanol extract of lessThan i greaterThan Coccinia grandis lessThan /i greaterThan exhibited a profound increase in THBP in all the regions of the gut and the percentage increase was 30, 13 and 13 at 75 ug/ml and was 43, 40.5 and 45 at 100 ug/ml in foregut, midgut and hindgut respectively. In the case of ethanol extract lessThan i greaterThan Coccinia grandis lessThan /i greaterThan at the concentration of 100 ug/ml lessThan i greaterThan Pseudomonas lessThan /i greaterThan sp., lessThan i greaterThan Proteus lessThan /i greaterThan sp., lessThan i greaterThan Achromobacter lessThan /i greaterThan sp., lessThan i greaterThan Flavobacterium lessThan /i greaterThan sp and lessThan i greaterThan E.coli lessThan /i greaterThan were found to increase in colony wise. No much variation was observed in the microbial population of lessThan i greaterThan Staphylococcus sp lessThan /i greaterThan . where as a profound elimination of microbial population in case of lessThan i greaterThan Micrococcus lessThan /i greaterThan sp., lessThan i greaterThan Streptococcus lessThan /i greaterThan sp. and lessThan i greaterThan Bacillus lessThan /i greaterThan sp. HEMALATHA.J, KALEENA .P.K AND K. VALIVITTAN gut flora, microbial analysis and C.grandis. 1184-1189