10.22376/ijpbs.2019.10.1.p1-12 Volume 6 Issue 1 2015 (January - March) lessThan i greaterThan Pseudomonas aeruginosa lessThan /i greaterThan , an important opportunistic pathogen causing a wide range of acute and chronic infections.The present study was undertaken to detect the Metallo β lactamase in isolated of lessThan i greaterThan Pseudomonas aeruginosa lessThan /i greaterThan which was isolated from wound infection and evaluated their susceptibility patterns.The presence of the MBL enzyme was detected by phenotypic confirmatiory tests are IMIPENEM-EDTA combined disc synergy test and Imipenem EDTA double disk synergy test .Out of 161 sample which were culture 39(24.2%)yielded the growth of Pseudomonas aeruginosa. Among the 39 Pseudomonas aeruginosa isolates 14(35.8%) were MBL produced P.aeruginosa and were also resistant to Ceftazidime/Clavulonic acid (CAC),Ceftazidime(CAZ), Amikacin(AK),Ciprofloxacin(CIP),Gentamicin(GEN).In our study out of 39 isolates, 14(35.4%) isolates are resistant to carbapenem and confirmed by disk potentiation test. The early detection may help in appropriate antimicrobial therapy and avoid the multidrug resistant strains.we recommend a routine surveillance on antibiotic resistance in every clinical microbiology laboratory in order to aid infection control. SANDHYA RANI T AND SWATHI.S Pseudomonas aeruginosa, Metallo β lactamase, Imipenem EDTA double disk synergy test and Ceftazidime. 1255-1259