10.22376/ijpbs.2019.10.1.p1-12 Volume 6 Issue 4 2015 (October - December) It has been established that nerve injury is accompanied by an increase in the content of lysophospholipids and an increased activity both Ca lessThan sup greaterThan 2 + lessThan /sup greaterThan - dependent and Ca lessThan sup greaterThan 2 + lessThan /sup greaterThan - independent phospholipase A lessThan sub greaterThan 2 lessThan /sub greaterThan . The introduction of the drug enhances the regenerative processes in damaged nerve that is manifested in the restoration of orderliness of the membranes of nerve fibers, as well as in the reduction of lysophospholipids and activity of Ca lessThan sup greaterThan 2 + lessThan /sup greaterThan - dependent phospholipase A lessThan sub greaterThan 2 lessThan /sub greaterThan . However, using the potassium hyaluronate does not lead to changes in the activity of Ca lessThan sup greaterThan 2 + lessThan /sup greaterThan - independent phospholipase A lessThan sub greaterThan 2 lessThan /sub greaterThan that likely indicates that Ca lessThan sup greaterThan 2+ lessThan /sup greaterThan - independent phospholipase A lessThan sub greaterThan 2 lessThan /sub greaterThan is not involved in the mechanism of nerve regeneration. Thus, it can be assumed that the acceleration of regeneration processes in damaged nerve conductor under the action of potassium hyaluronate is likely mediated by the functioning of Ca lessThan sup greaterThan 2+ lessThan /sup greaterThan - dependent phospholipase A lessThan sub greaterThan 2 lessThan /sub greaterThan . V. V. REVIN, M. V. ISAKINA, S. I. PINYAEV,N. V. REVINA AND A. A. MOROZOVA Phospholipase A2, potassium hyaluronate, lysophospholipids, nerve regeneration, Raman scattering spectroscopy. 512-520