10.22376/ijpbs.2019.10.1.p1-12 Volume 6 Issue 4 2015 (October - December) The global consciousness reveals about the use of eco-friendly natural dyes in textiles and food industries instead of hazardous and carcinogenic synthetic dyes. Many of the plant materials, from which natural dyes are obtained, found to have some medicinal values. During the present study, dying materials were prepared from leaves of lessThan i greaterThan Morinda citrifolia lessThan /i greaterThan L. and lessThan i greaterThan Terminalia catappa lessThan /i greaterThan L. The antimicrobial potential of the two different dyed fabrics was studied against lessThan i greaterThan Klebsiella pneumoniae, Escherichia coli, Candida albicans lessThan /i greaterThan and lessThan i greaterThan Aspergillus lessThan /i greaterThan sp. The dye obtained from leaves of lessThan i greaterThan Morinda citrifolia lessThan /i greaterThan was found to be more effective by exhibiting maximum zone of inhibition as compared to lessThan i greaterThan Terminalia catappa lessThan /i greaterThan . The fabrics impregnated with two natural dyes resulted in the maximum inhibition rate (67 %) against lessThan i greaterThan Candida albicans lessThan /i greaterThan as observed in the silk samples dyed with lessThan i greaterThan Morinda citrifolia lessThan /i greaterThan . The dyed fabrics also showed reasonably good wash fastness; hence have practical potential for adding antibacterial properties along with vibrant colours to textiles of medical and other delicate uses. BASANTI MAJHI, KUNJA BIHARI SATAPATHY AND SAGAR KUMAR MISHRA Antimicrobial effectiveness; Natural dye; Morinda citrifolia L.; Terminalia catappa L.; Colour fastness; Silk fabric 836-843