10.22376/ijpbs.2019.10.1.p1-12 Volume 2 Issue 1 2011 (January - March) Some Pathogens are resistant to various antimicrobial agents. The essential oils/terpenoids were found to exhibit antimicrobial activity against P.aeruginosa, E.coli, S.aureus and C.albicans. In the present study GRAS (generally recognized as safe) terpenoids are grouped according to the structure and their MIC (minimum inhibitory concentration), studied to specify the activity of terpenes against P.aeruginosa, E.coli, S.aureus and C.albicans pathogens. It is concluded that the terpenoid from natural resources could combat the resistant pathogens and make environmentally benign antimicrobial agents.  Neerja Gupta,Goldy Saxena,S.S.Kalra MIC, terpenoids, antimicrobial agents. 87-91