10.22376/ijpbs.2019.10.1.p1-12 Volume 7 Issue 4 2016 (October - December) Globally available folklore medicines are consumed by people as food, without scientific validation. Aim of the present study is to evaluate the antiulcer and antioxidant activity of traditional herbs. Physicochemical analysis, preliminary phytochemical analysis and quantitative analysis of aerial parts from lessThan i greaterThan Solanum nigrum lessThan /i greaterThan and lessThan i greaterThan Cynodon dactylon lessThan /i greaterThan were carried out. the free radical scavenging activity of aqueous extracts of both herbs was carried out by adopting different assays. Antiulcer activity of both extracts was evaluated by H lessThan sup greaterThan + lessThan /sup greaterThan K lessThan sup greaterThan + lessThan /sup greaterThan ATP ase inhibitory activity. Results of the present study reveal that the collected herb was pure, nutritionally rich in nature. IC lessThan sub greaterThan 50 lessThan /sub greaterThan values reveal that aqueous extract from lessThan i greaterThan Solanum nigrum lessThan /i greaterThan is a potent inhibitor of lipid peroxidation than lessThan i greaterThan Cynodon dactylon lessThan /i greaterThan (p lessThan 0.05). Reducing potential,free radical scavenging activity and H lessThan sup greaterThan + lessThan /sup greaterThan K lessThan sup greaterThan + lessThan /sup greaterThan ATP ase inhibitory activity of both extracts did not differ significantly. To conclude, both herbs are equally potent antioxidants and proton pump inhibitors. K.RAJASEKAR AND K.GAYATHRI antioxidant, antiulcer, physicochemical analysis, phytochemical analysis 67-72