10.22376/ijpbs.2019.10.1.p1-12 Volume 7 Issue 4 2016 (October - December) Lamiaceae herbs known for their culinary properties are a rich source of potentially health-beneficial antioxidant polyphenols. The objective of this investigation was to evaluate and prove the lessThan i greaterThan in vitro lessThan /i greaterThan antioxidant activity of five different extracts of aerial parts of the plant lessThan i greaterThan Leucas aspera, lessThan /i greaterThan belonging to the family Lamiaceae on different models namely the DPPH free radical scavenging assay, Fe lessThan sup greaterThan 2 lessThan b greaterThan + lessThan /b greaterThan lessThan /sup greaterThan lessThan b greaterThan - lessThan /b greaterThan ascorbate induced lipid peroxidation, Nitric oxide scavenging activity, Total antioxidant equivalence and Hydroxyl radical scavenging activity by standardized methods. The results showed the ethanolic and hydroalcoholic extracts of lessThan i greaterThan Leucas aspera lessThan /i greaterThan (EELA and HAELA) to exhibit maximum inhibition of free radical formation followed by EAELA, the ethyl acetate extract. The least antioxidant potential was exhibited by HELA and CELA, the n-hexane and chloroform extracts of lessThan i greaterThan Leucas aspera lessThan /i greaterThan . The potential antioxidant activities lessThan i greaterThan in vitro lessThan /i greaterThan may indicate their therapeutic and related beneficial properties in oxidative stress, a condition underlying many disorders.  K.G.KRIPA AND D.CHAMUNDEESWARI Leucas aspera, Free radicals, Lamiaceae, Antioxidants 171-178