10.22376/ijpbs.2019.10.1.p1-12 Volume 7 Issue 4 2016 (October - December) Pomegranate ( lessThan i greaterThan Punica granatum lessThan /i greaterThan L.) has been used for ages in many civilizations for the prevention and treatment of a varied number of health maladies such as Cancer, diabetes, inflammation, dental plaque, dysentery, and to fight malarial parasites and intestinal infections. It is an important source of bioactive compounds such as Ellagitannins and the Punicalagin. In the present study, potential biological activities of aqueous peel extract of pomegranate were carried out. Antibacterial activity was studied against lessThan i greaterThan Escherichia coli lessThan /i greaterThan , lessThan i greaterThan Pseudomonas aeruginosa lessThan /i greaterThan , lessThan i greaterThan Staphylococcus aureus lessThan /i greaterThan , lessThan i greaterThan and Salmonella typhii lessThan /i greaterThan ; Antifungal activity against lessThan i greaterThan Aspergillus niger and Aspergillus flavus lessThan /i greaterThan . Antioxidative study was evaluated by DPPH and FRAP assay. Antimicrobial study reveals all the tested bacterial and fungal strains were susceptible to aqueous peel extract as dose dependent manner. Maximum activity was observed in high concentration of extracts. DPPH and FRAP assay showed potential antioxidative activity due to the presence of various flavonoids. R.S.ARVIND BHARANI AND S.KARTHICK RAJA NAMASIVAYAM Pomegranates, Aqueous peel extract, antimicrobial, antioxidant. 282-290