International Journal of Pharma and Bio Sciences
ijpbs.net
editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com
10.22376/ijpbs.2019.10.1.p1-12
Volume 7 Issue 4
2016 (October - December)
Sulphur dioxid induced hematotoxicity and its melioration by emblicaofficinalis in rattusnorvegicus (berkenhout)
Present study was designed to investigate the adverse effects of SO lessThan sub greaterThan 2 lessThan /sub greaterThan on hematology in terms of total leucocyte count [TLC] and differential leucocyte count [DLC] – monocyte count, lymphocyte count, neutrophil count, basophil count and eosinophil count, besides, modulatory effects of lessThan i greaterThan Emblica officinalis lessThan /i greaterThan (Amla) in albino rat. The rats of both sexes were kept in standard laboratory conditions and grouped as- control group (1) kept away from exposed rats for 30 & 60 days, experimental group (2) exposed to 80ppm SO lessThan sub greaterThan 2 lessThan /sub greaterThan gas (1h/d) for 30 & 60 days and experimental group (3) exposed to 80ppm SO lessThan sub greaterThan 2 lessThan /sub greaterThan gas (1h/d) with oral supplementation of aqueous extract of lessThan i greaterThan Emblica officinalis lessThan /i greaterThan (200mg/rat/day) for 30 & 60 days. The findings of the present study showed a significant increase in total leucocyte count, besides, decrease in differential leucocyte count with an increase in neutrophil count is the result of inflammation due to toxic action of SO lessThan sub greaterThan 2 lessThan /sub greaterThan gas. However, SO lessThan sub greaterThan 2 lessThan /sub greaterThan induced alterations were meliorated after supplementation of aqueous extract of lessThan i greaterThan Emblica officinalis lessThan /i greaterThan due to its antioxidant and anti-inflammatory activity, in albino rats.
Dr. MADHURI YADAV
Emblica officinalis, SO2, Albino rat, TLC, DLC
922-927