10.22376/ijpbs.2019.10.1.p1-12 Volume 2 Issue 1 2011 (January - March) The different plant extracts were initially screened for their anti microbial activity and then, were extracted in different solvents. The extracts were tested against two Gram positive and four Gram negative organisms by using the standard disc diffusion method. Phytochemical analysis were also carried out that included Assay of Withanoloides for Withania somnifera (Ashwagandha) and Assay of Tannin and Saponin for Hemidesmus indicus (Sariva) and Assay of Gingerol in Zingiber officinale (Shunthi Rhizome). The actives of Zingiber officinale were also confirmed by the HPLC method. They were also screened for the presence of both Heavy metals and microbial analysis by standard protocols.  Bhavna Solanki,Kruti Pandya,Kunal Maniar,Nilesh Gurav,Dr Surendra Bhatt Anti microbial activity, HPLC, disc diffusion method, Mc Farland’s turbidity, heavy metal, microbial analysis. 772-779